Welcome to the forum.
I am assuming you are aware that LE is in beta, is generally unoptimised and has known performance related instability. You havent really provided enough info - system info via a dxdiag report or game settings via the le_graphicsmanager.ini - but I can assure you that from what I can see from info in the logs you have provided, your hardware would not be running the game on Ultra quality at high FPS without some sort of instability.
It is a combination of the games current unoptimised state and your specific hardware and settings. For example, if you are not limiting the game in some way, it will attempt to max out your GPU and as a consequence, become unstable when the game demands more in certain situations. And thats not even considering the instances where the game is more demanding of the CPU directly. I.e. a maxed out GPU may be handling ok, but additional load on the CPU can cause a double whammy and make the game crash.
Certain settings like Ultra quality and high or no FPS limit (e.g. 144hz vsync / 144fps) are 100% know to be causes of issues and in most cases dropping these down a notch or two will improve stability dramatically with (imho) very little noticeable difference in playing LE. remember its not a First Person Shooter where every fps matters.
As a reference point. I run an old 1060.i5-7500 setup on Very Low settings with 1080p at 60fps and I have crashed less than a half dozen times in over 2k hours of nromal play. While specifically testing, ff i set the quality to Ultra, I crash - usually by the first or second map. If I set the FPS limit beyond 100fps, I crah or the game regularly freezes.
The above are usually the main issues, but there are also the issue of GPU drivers & OS patches. Old or corrupted GPU drivers are often the cause of instability in LE. As are Windows OS patches. A simple CLEAN GPU driver install can sometimes be the solution to someones problem.
Another potential cause of instability, is other applications running at the time of testing LE. Even things like Steam Overlays (which LE doesnt use) have caused problems on certain setups and should not be used.
The logs you have provided dont give much to work on specifically. The game is struggling with FMOD (which is the audio component) of the Unity Game Engine LE uses - all audio issues are either CPU or driver related, but it could also be that the game is generally struggling because of your high settings (?).
There may also be something else going on on your system - i.e. I have no idea what drivers you are using, if Windows is reporting any other issues that could be related. I would recommend checking View Reliability History on your system to see if there are OS level errors being reported that could be involved.
My simplest answer (having explained things above):
Make sure that your OS is patched and there are no failed updates
Make sure your GPU driver is no older than 3 months and has been installed with a CLEAN driver installation - not an upgrade. Upgrade installs dont usually resolve GPU driver file problems.
Dont run anything else while testing LE. Disable things like Steam Overlays etc.
Set the game to 1080p, 60fps framerate limited, All quality settings on Very Low and special features on thier lowest settings or disabled - play at these settings - if the game is stable, then its simply a question of you chosing settings where you find a suitable compromise between quality, resolution, fps and stability. Change settings and test incrementally. Without specific testing and watching what your GPU usage % are during play, I would guess that High quality @ 1080p and 100fps is likely to be stable on your setup.