If they hit me with poison, the PC will restart
Full restart? Woah. That sucks mate.
Some people who have experienced crashes find it is resolved by:
- deleting graphics ini file https://support.lastepoch.com/hc/en-us/articles/1260805163370-The-Graphics-ini-File
- getting latest drivers for their graphics card
- verifying game file integrity through Steam client and/or reinstalling the game
I hope one of these works for you
Sorry but I laugh a lot reading your message 
Imagine developpers be like : “It’s not a bug, it’s a new gameplay function. Welcome to our new hardcore mode, if you’re touch by any pre-defined kind of damage, your pc is restarting, erasing all of your datas. Welcomes to hell.”
Good luck resolving your problem mate.