Whatever mouseclick looting code you have for Glyphs/Runes/Shards, make clicking on loot function exactly the same way.
Looting Glyphs/Runes/Shards is a pleasure. Looting items is a colossal pain.
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Edit for clarity: This is not asking for item vacuuming. This is asking for responsive clicking of items, the way shards are responsive when you click on them. Clicking on an item only works 1/4 of the time.