I have a level 40 void knight, using abyssal orbs. When I have the maximum number of abyssal orbs out the game will crash shortly thereafter, usually in less than a minute, sometimes in seconds.
I have a decent computer, Ryzen 5 3600, Asus Strix 3080, Asus x570 motherboard, 16gb 3200 ram, Corsair 850w psu. Running the game on medium to low settings with framerate capped to 60. Have tried running it in admin mode and set the priority in task manager to high.